RplP

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  • Description: ribosomal protein L16,binding of L16 to the 50S subunit is required for the stimulation of RbgA GTPase activity, for release of RbgA from the ribosome, and for the conversion of the intermediate to the complete 50S subunit

Gene name rplP
Synonyms
Essential yes PubMed
Product ribosomal protein L16
Function translation
Gene expression levels in SubtiExpress: rplP
Interactions involving this protein in SubtInteract: RplP
MW, pI 16 kDa, 10.88
Gene length, protein length 432 bp, 144 aa
Immediate neighbours rpsC, rpmC
Sequences Protein DNA DNA_with_flanks
Genetic context
RplP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RplP expression.png















Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01230

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

  • the protein is significantly underrepresented in 45S assembly intermediates that accumulate upon depletion of RbgA PubMed

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References