YacL

• Description: general stress protein, survival of salt and ethanol stresses
  
  

Gene name	yacL
Synonyms
Essential	no
Product	unknown
Function	survival of salt and ethanol stresses
Gene expression levels in SubtiExpress: yacL
MW, pI	40 kDa, 4.97
Gene length, protein length	1098 bp, 366 aa
Immediate neighbours	disA, ispD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigB regulon, SigM regulon

The gene

Basic information

• Locus tag: BSU00890

Database entries

• BsubCyc: BSU00890

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: TRAM domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU00890

• Structure:

• UniProt: Q06754

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yacL-ispD-ispF PubMed

• Expression browser: yacL PubMed

• Sigma factor: SigB PubMed, SigM PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Adrian J Jervis, Penny D Thackray, Chris W Houston, Malcolm J Horsburgh, Anne Moir
SigM-responsive genes of Bacillus subtilis and their promoters.
J Bacteriol: 2007, 189(12);4534-8
[PubMed:17434969] [WorldCat.org] [DOI] (P p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

A Petersohn, J Bernhardt, U Gerth, D Höper, T Koburger, U Völker, M Hecker
Identification of sigma(B)-dependent genes in Bacillus subtilis using a promoter consensus-directed search and oligonucleotide hybridization.
J Bacteriol: 1999, 181(18);5718-24
[PubMed:10482513] [WorldCat.org] [DOI] (P p)