YbgB

• Description: putative immunity protein
  
  

Gene name	ybgB
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: ybgB
MW, pI	10 kDa, 8.47
Gene length, protein length	273 bp, 91 aa
Immediate neighbours	gamR, ybgE
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell envelope stress proteins (controlled by SigM, V, W, X, Y), toxins, antitoxins and immunity against toxins, membrane proteins

This gene is a member of the following regulons

SigY regulon, GamR regulon

The gene

Basic information

• Locus tag: BSU02380

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): SdpI, YfhL

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O31460

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • gamR-ybgB PubMed
  • ybgB PubMed

• Expression browser: ybgB PubMed

• Sigma factor:
  • gamR: SigA PubMed
  • ybgB: SigY PubMed

• Regulation:
  • induced by glucosamine (gamR) PubMed

• Regulatory mechanism:
  • YbgA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Isabelle Gaugué, Jacques Oberto, Jacqueline Plumbridge
Regulation of amino sugar utilization in Bacillus subtilis by the GntR family regulators, NagR and GamR.
Mol Microbiol: 2014, 92(1);100-15
[PubMed:24673833] [WorldCat.org] [DOI] (I p)

Isabelle Gaugué, Jacques Oberto, Harald Putzer, Jacqueline Plumbridge
The use of amino sugars by Bacillus subtilis: presence of a unique operon for the catabolism of glucosamine.
PLoS One: 2013, 8(5);e63025
[PubMed:23667565] [WorldCat.org] [DOI] (I e)

Min Cao, Letal Salzberg, Ching Sung Tsai, Thorsten Mascher, Carla Bonilla, Tao Wang, Rick W Ye, Leticia Márquez-Magaña, John D Helmann
Regulation of the Bacillus subtilis extracytoplasmic function protein sigma(Y) and its target promoters.
J Bacteriol: 2003, 185(16);4883-90
[PubMed:12897008] [WorldCat.org] [DOI] (P p)