Ipi

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  • Description: intracellular proteinase inhibitor

Gene name ipi
Synonyms
Essential no
Product intracellular proteinase inhibitor
Function control of intracellular proteolysis
Gene expression levels in SubtiExpress: ipi
MW, pI 13 kDa, 4.692
Gene length, protein length 357 bp, 119 aa
Immediate neighbours yitT, yizC
Sequences Protein DNA DNA_with_flanks
Genetic context
Ipi context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Ipi expression.png
























Categories containing this gene/protein

proteolysis

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU11130

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Daniel J Rigden, Qingping Xu, Yuanyuan Chang, Ruth Y Eberhardt, Robert D Finn, Neil D Rawlings
The first structure in a family of peptidase inhibitors reveals an unusual Ig-like fold.
F1000Res: 2013, 2;154
[PubMed:24555072] [WorldCat.org] [DOI] (P e)

Qingxin Li, Angela Shuyi Chen, Shovanlal Gayen, Congbao Kang
¹H, ¹³C and ¹⁵N chemical shift assignments for an intracellular proteinase inhibitor of Bacillus subtilis.
Biomol NMR Assign: 2013, 7(2);129-32
[PubMed:22585087] [WorldCat.org] [DOI] (I p)

Y Shiga, H Yamagata, S Udaka
Characterization of the gene encoding an intracellular proteinase inhibitor of Bacillus subtilis and its role in regulation of the major intracellular proteinase.
J Bacteriol: 1993, 175(22);7130-7
[PubMed:8226659] [WorldCat.org] [DOI] (P p)