PksA

• Description: transcriptional regulator (TetR family), not involved in the regulation of the pks operon!
  
  

Gene name	pksA
Synonyms
Essential	no
Product	transcriptional regulator (TetR family)
Function	unknown
Gene expression levels in SubtiExpress: pksA
MW, pI	23 kDa, 6.436
Gene length, protein length	615 bp, 205 aa
Immediate neighbours	ymcC, pksB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control

The gene

Basic information

• Locus tag: BSU17080

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: TetR family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34381

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: pksA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Leslie Cuthbertson, Justin R Nodwell
The TetR family of regulators.
Microbiol Mol Biol Rev: 2013, 77(3);440-75
[PubMed:24006471] [WorldCat.org] [DOI] (I p)

Original publications

Carol Vargas-Bautista, Kathryn Rahlwes, Paul Straight
Bacterial competition reveals differential regulation of the pks genes by Bacillus subtilis.
J Bacteriol: 2014, 196(4);717-28
[PubMed:24187085] [WorldCat.org] [DOI] (I p)