PhrG

• Description: response regulator aspartate phosphatase (RapG) regulator
  
  

Gene name	phrG
Synonyms	yycL
Essential	no
Product	phosphatase (RapG) regulator
Function	control of DegU activity
Gene expression levels in SubtiExpress: phrG
Interactions involving this protein in SubtInteract: PhrG
MW, pI	4 kDa, 9.017
Gene length, protein length	114 bp, 38 aa
Immediate neighbours	rapG, rocF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, quorum sensing, short peptides

This gene is a member of the following regulons

CcpA regulon, RghR regulon, SigH regulon

The gene

Basic information

• Locus tag: BSU40310

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binds to RapG, this results in the inability of RapG to interact with DegU PubMed

• Protein family: phr family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • PhrG-RapG PubMed

• Localization:

Database entries

• Structure:

• UniProt: O32295

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rapG-phrG PubMed

• Expression browser: phrG PubMed

• Sigma factor: SigA PubMed, SigH PubMed

• Regulation:
  • repressed by SinR PubMed
  • repressed by RghR PubMed
  • repressed by glucose (4.8-fold) (CcpA) PubMed

• Regulatory mechanism:
  • SinR: transcription repression PubMed
  • RghR: transcription repression PubMed
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: