YqaM

• Description: similar to phage-related protein, skin-element
  
  

Gene name	yqaM
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yqaM
Interactions involving this protein in SubtInteract: YqaM
MW, pI	35 kDa, 5.386
Gene length, protein length	939 bp, 313 aa
Immediate neighbours	yqzO, yqaL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

Skin element

This gene is a member of the following regulons

SknR regulon

The gene

Basic information

• Locus tag: BSU26260

Phenotypes of a mutant

• overexpression of YqaM causes cell filamentation and abnormal chromosome segregation PubMed
• overexpression of YqaM inhibits initiation DNA replication, perhaps due to the interaction with DnaC PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): XkdC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YqaM-DnaC PubMed

• Localization: Cytoplasm (Homogeneous) PubMed

Database entries

• Structure:

• UniProt: P45910

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN PubMed

• Expression browser: yqaM PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • not expressed during normal growth (SknR) PubMed

• Regulatory mechanism:
  • SknR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tatsu Kimura, Yukie Amaya, Kazuo Kobayashi, Naotake Ogasawara, Tsutomu Sato
Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.
J Bacteriol: 2010, 192(23);6209-16
[PubMed:20889742] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Marie-Françoise Noirot-Gros, Etienne Dervyn, Ling Juan Wu, Peggy Mervelet, Jeffery Errington, S Dusko Ehrlich, Philippe Noirot
An expanded view of bacterial DNA replication.
Proc Natl Acad Sci U S A: 2002, 99(12);8342-7
[PubMed:12060778] [WorldCat.org] [DOI] (P p)