YbdK

• Description: two-component sensor kinase
  
  

Gene name	ybdK
Synonyms
Essential	no
Product	two-component sensor kinase
Function	unknown
Gene expression levels in SubtiExpress: ybdK
Interactions involving this protein in SubtInteract: YbdK
MW, pI	37 kDa, 5.212
Gene length, protein length	960 bp, 320 aa
Immediate neighbours	ybdJ, ybzI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein modification, transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

• Locus tag: BSU02010

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of YbdJ

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain

• Modification: autophosphorylation on a His residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YbdK-YbdJ

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O31433

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ybdK DBTBS

• Expression browser: ybdK PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism: ComK: positive regulation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Young Pil Kim, Kwon Joo Yeo, Myung Hee Kim, Young-Chang Kim, Young Ho Jeon
Structural characterization of the intra-membrane histidine kinase YbdK from Bacillus subtilis in DPC micelles.
Biochem Biophys Res Commun: 2010, 391(3);1506-11
[PubMed:20035725] [WorldCat.org] [DOI] (I p)

Mitsuo Ogura, Hirotake Yamaguchi, Kazuo Kobayashi, Naotake Ogasawara, Yasutaro Fujita, Teruo Tanaka
Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK.
J Bacteriol: 2002, 184(9);2344-51
[PubMed:11948146] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)