CsbB

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  • Description: putative bactoprenol glycosyltransferase, general stress protein, required for protection against paraquat stress

Gene name csbB
Synonyms yfhN
Product putative bactoprenol glycosyltransferase
Function survival of stress conditions
Gene expression levels in SubtiExpress: csbB
MW, pI 37 kDa, 9.199
Gene length, protein length 987 bp, 329 aa
Immediate neighbours yfhM, yfhO
Sequences Protein DNA DNA_with_flanks
Genetic context
CsbB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CsbB expression.png















Categories containing this gene/protein

general stress proteins (controlled by SigB), cell envelope stress proteins (controlled by SigM, V, W, X, Y), resistance against oxidative and electrophile stress, membrane proteins

This gene is a member of the following regulons

SigB regulon, SigX regulon

The gene

Basic information

  • Locus tag: BSU08600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: GtrB subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hiromi Inoue, Daisuke Suzuki, Kei Asai
A putative bactoprenol glycosyltransferase, CsbB, in Bacillus subtilis activates SigM in the absence of co-transcribed YfhO.
Biochem Biophys Res Commun: 2013, 436(1);6-11
[PubMed:23632331] [WorldCat.org] [DOI] (I p)

Alexander Reder, Dirk Höper, Ulf Gerth, Michael Hecker
Contributions of individual σB-dependent general stress genes to oxidative stress resistance of Bacillus subtilis.
J Bacteriol: 2012, 194(14);3601-10
[PubMed:22582280] [WorldCat.org] [DOI] (I p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

X Huang, J D Helmann
Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search.
J Mol Biol: 1998, 279(1);165-73
[PubMed:9636707] [WorldCat.org] [DOI] (P p)

S Akbar, C W Price
Isolation and characterization of csbB, a gene controlled by Bacillus subtilis general stress transcription factor sigma B.
Gene: 1996, 177(1-2);123-8
[PubMed:8921856] [WorldCat.org] [DOI] (P p)