NagR

From SubtiWiki
Revision as of 16:41, 24 May 2013 by Jstuelk (talk | contribs)
Jump to: navigation, search
Gene name nagR
Synonyms yvoA
Essential no
Product transcriptional regulator (GntR family)
Function probably regulator of the putative nagA-nagB-yvoA operon
Gene expression levels in SubtiExpress: nagR
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism, Murein recycling
MW, pI 27 kDa, 6.768
Gene length, protein length 729 bp, 243 aa
Immediate neighbours nagB, yvnB
Sequences Protein DNA DNA_with_flanks
Genetic context
YvoA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NagR expression.png















Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

NagR regulon

The NagR regulon:

The gene

Basic information

  • Locus tag: BSU35030

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription repression of nagP and of the putative nagA-nagB-nagR operon in the absence of N-acetylglycosamine PubMed, weak repression of yflG PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information: K(D) for N-acetylglucosamine-6-phosphate: 1 mM PubMed
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • N-acetylglucosamine-6-phosphate acts as the molecular inducer PubMed
    • glucosamine-6-phosphate acts as the molecular inducerPubMed

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced in the presence of N-acetylglucosamine (NagR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References