Dps

• Description: iron storage protein, general stress protein, resistance against ethanol stress and survival at low temperatures
  
  

Gene name	dps
Synonyms	ytkB
Essential	no
Product	mini-ferritin
Function	iron storage
Gene expression levels in SubtiExpress: dps
MW, pI	16 kDa, 4.444
Gene length, protein length	435 bp, 145 aa
Immediate neighbours	ytkC, ytzI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

acquisition of iron, iron metabolism, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU30650

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: dps family (according to Swiss-Prot)

• Paralogous protein(s): MrgA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P80879

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dps PubMed

• Expression browser: dps PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Emilia Chiancone, Pierpaolo Ceci, Andrea Ilari, Frederica Ribacchi, Simonetta Stefanini
Iron and proteins for iron storage and detoxification.
Biometals: 2004, 17(3);197-202
[PubMed:15222465] [WorldCat.org] [DOI] (P p)

Original publications

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

H Antelmann, S Engelmann, R Schmid, A Sorokin, A Lapidus, M Hecker
Expression of a stress- and starvation-induced dps/pexB-homologous gene is controlled by the alternative sigma factor sigmaB in Bacillus subtilis.
J Bacteriol: 1997, 179(23);7251-6
[PubMed:9393687] [WorldCat.org] [DOI] (P p)

M Bozzi, G Mignogna, S Stefanini, D Barra, C Longhi, P Valenti, E Chiancone
A novel non-heme iron-binding ferritin related to the DNA-binding proteins of the Dps family in Listeria innocua.
J Biol Chem: 1997, 272(6);3259-65
[PubMed:9013563] [WorldCat.org] [DOI] (P p)