YtbE

• Description: putative aldo/keto reductase, may be involved in detoxification
  
  

Gene name	ytbE
Synonyms
Essential	yes PubMed
Product	putative aldo/keto reductase
Function	unknown
Gene expression levels in SubtiExpress: ytbE
MW, pI	31 kDa, 4.786
Gene length, protein length	840 bp, 280 aa
Immediate neighbours	ytbD, ytaG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

poorly characterized/ putative enzymes, membrane proteins, essential genes

The gene

Basic information

• Locus tag: BSU29050

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Nudix hydrolase, aldo/keto reductase family (according to Swiss-Prot)

• Paralogous protein(s): YvgN

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure: 3A3D

• UniProt: O34678

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ytbE PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Jian Lei, Yan-Feng Zhou, Lan-Fen Li, Xiao-Dong Su
Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis.
Protein Sci: 2009, 18(8);1792-800
[PubMed:19585557] [WorldCat.org] [DOI] (I p)

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)