BlyA

• Description: N-acetylmuramoyl-L-alanine amidase
  
  

Gene name	blyA
Synonyms	yomC
Essential	no
Product	N-acetylmuramoyl-L-alanine amidase
Function	SPß-mediated lysis
Gene expression levels in SubtiExpress: blyA
MW, pI	39 kDa, 9.935
Gene length, protein length	1101 bp, 367 aa
Immediate neighbours	yomD, bhlA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall degradation/ turnover, SP-beta prophage

The gene

Basic information

• Locus tag: BSU21410

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: contains an amidase_2 domain (like CwlA, CwlH, XlyA, XlyB)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31982

• KEGG entry: [2]

• E.C. number: 3.5.1.28

Expression and regulation

• Operon:

• Expression browser: blyA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Alexandre Regamey, Dimitri Karamata
The N-acetylmuramoyl-L-alanine amidase encoded by the Bacillus subtilis 168 prophage SP beta.
Microbiology (Reading): 1998, 144 ( Pt 4);885-893
[PubMed:9579063] [WorldCat.org] [DOI] (P p)