YloN

• Description: similar to rRNA adenosine methyltransferase for modification of 23S rRNA
  
  

Gene name	yloN
Synonyms
Essential	no
Product	rRNA methyltransferase
Function	rRNA modification
Gene expression levels in SubtiExpress: yloN
MW, pI	41 kDa, 6.788
Gene length, protein length	1089 bp, 363 aa
Immediate neighbours	yloM, prpC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation

The gene

Basic information

• Locus tag: BSU15750

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: RlmN family (according to Swiss-Prot), SAM enzyme superfamily

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34617

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yloN PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A819 ( yloN::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Perry A Frey, Adrian D Hegeman, Frank J Ruzicka
The Radical SAM Superfamily.
Crit Rev Biochem Mol Biol: 2008, 43(1);63-88
[PubMed:18307109] [WorldCat.org] [DOI] (I p)

Seok-Ming Toh, Liqun Xiong, Taeok Bae, Alexander S Mankin
The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA.
RNA: 2008, 14(1);98-106
[PubMed:18025251] [WorldCat.org] [DOI] (I p)