YkkE

• Description: formyltetrahydrofolate deformylase
  
  

Gene name	ykkE
Synonyms	purU
Essential	no
Product	formyltetrahydrofolate deformylase
Function	purine nucleotide synthesis
Gene expression levels in SubtiExpress: ykkE
MW, pI	34 kDa, 5.949
Gene length, protein length	900 bp, 300 aa
Immediate neighbours	ykkD, proB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides

The gene

Basic information

• Locus tag: BSU13110

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + H₂O = formate + tetrahydrofolate (according to Swiss-Prot)

• Protein family: ACT domain (according to Swiss-Prot)

• Paralogous protein(s): PurN

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34990

• KEGG entry: [2]

• E.C. number: 3.5.1.10

Expression and regulation

• Operon:

• Expression browser: ykkE PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: