HelP

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  • Description: helicase processivity factor

Gene name ydcP
Synonyms ydcP
Essential no
Product helicase processivity factor
Function conjugation and replication of ICEBs1
Gene expression levels in SubtiExpress: helP
MW, pI 13 kDa, 5.309
Gene length, protein length 378 bp, 126 aa
Immediate neighbours ydcO, ydcQ
Sequences Protein DNA DNA_with_flanks
Genetic context
YdcP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YdcP expression.png















Categories containing this gene/protein

mobile genetic elements

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04850

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • enables the host-encoded helicase PcrA to unwind the double-stranded ICEBs1 DNA PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jacob Thomas, Catherine A Lee, Alan D Grossman
A conserved helicase processivity factor is needed for conjugation and replication of an integrative and conjugative element.
PLoS Genet: 2013, 9(1);e1003198
[PubMed:23326247] [WorldCat.org] [DOI] (I p)

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)