TmrB

• Description: tunicamycin resistance protein, ATP-binding membrane protein
  
  

Gene name	tmrB
Synonyms
Essential	no
Product	tunicamycin resistance protein
Function	resistance to tunicamycin
Gene expression levels in SubtiExpress: tmrB
MW, pI	22 kDa, 9.714
Gene length, protein length	591 bp, 197 aa
Immediate neighbours	nadE, aroK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against toxins/ antibiotics, membrane proteins

The gene

Basic information

• Locus tag: BSU03140

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P12921

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tmrB (according to DBTBS)

• Expression browser: tmrB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Y Noda, K Yoda, A Takatsuki, M Yamasaki
TmrB protein, responsible for tunicamycin resistance of Bacillus subtilis, is a novel ATP-binding membrane protein.
J Bacteriol: 1992, 174(13);4302-7
[PubMed:1624425] [WorldCat.org] [DOI] (P p)