YvaK

• Description: general stress protein, similar to carboxylesterase
  
  

Gene name	yvaK
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yvaK
MW, pI	28 kDa, 4.992
Gene length, protein length	744 bp, 248 aa
Immediate neighbours	rnr, secG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), poorly characterized/ putative enzymes, sporulation proteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU33620

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: A carboxylic ester + H₂O = an alcohol + a carboxylate (according to Swiss-Prot)

• Protein family: lipase/esterase LIP3/bchO family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1TQH (Geobacillus stearothermophilus)

• UniProt: O32232

• KEGG entry: [2]

• E.C. number: 3.1.1.1

Expression and regulation

• Operon:
  • secG-yvaK-rnr-smpB-ssrA PubMed
  • yvaK-rnr-smpB-ssrA PubMed

• Expression browser: yvaK PubMed

• Sigma factor:
  • yvaK: SigB PubMed

• Regulation:
  • yvaK: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ji-Hyun Shin, Chester W Price
The SsrA-SmpB ribosome rescue system is important for growth of Bacillus subtilis at low and high temperatures.
J Bacteriol: 2007, 189(10);3729-37
[PubMed:17369301] [WorldCat.org] [DOI] (P p)

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)