HelD

• Description: DNA 3'-5' helicase IV
  
  

Gene name	helD
Synonyms	yvgS
Essential	no
Product	DNA 3'-5' helicase IV
Function	DNA repair and recombination
Gene expression levels in SubtiExpress: helD
MW, pI	89 kDa, 6.083
Gene length, protein length	2322 bp, 774 aa
Immediate neighbours	cysI, yvgT
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination

The gene

Basic information

• Locus tag: BSU33450

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: UvrD subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • HelD interacts with the RNA polymerase PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32215

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: helD PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A899 ( helD::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

B Carrasco, S Fernández, M A Petit, J C Alonso
Genetic recombination in Bacillus subtilis 168: effect of DeltahelD on DNA repair and homologous recombination.
J Bacteriol: 2001, 183(19);5772-7
[PubMed:11544244] [WorldCat.org] [DOI] (P p)