PapA
Revision as of 10:42, 14 May 2013 by 134.76.70.252 (talk)
- Description: Xaa-Pro amino-peptidase
| Gene name | papA |
| Synonyms | yqhT |
| Essential | no |
| Product | Xaa-Pro amino-peptidase |
| Function | degradation of proline-containing peptides |
| Gene expression levels in SubtiExpress: papA | |
| Metabolic function and regulation of this protein in SubtiPathways: Alternative nitrogen sources | |
| MW, pI | 37 kDa, 4.83 |
| Gene length, protein length | 1059 bp, 353 aa |
| Immediate neighbours | efp, yqhS |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
utilization of nitrogen sources other than amino acids, coping with hyper-osmotic stress
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24460
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase M24B family (according to Swiss-Prot)
- Paralogous protein(s): PapB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 3Q6D (the B. anthracis enzyme, 65% identity, 82% similarity)
- UniProt: P54518
- KEGG entry: [2]
- E.C. number: 3.4.11.9
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: available in the Erhard Bremer lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Erhard Bremer, Marburg University, Germany Homepage
Your additional remarks
References
Adrienne Zaprasis, Jeanette Brill, Marietta Thüring, Guido Wünsche, Magnus Heun, Helena Barzantny, Tamara Hoffmann, Erhard Bremer
Osmoprotection of Bacillus subtilis through import and proteolysis of proline-containing peptides.
Appl Environ Microbiol: 2013, 79(2);576-87
[PubMed:23144141]
[WorldCat.org]
[DOI]
(I p)
