LspA

• Description: signal peptidase II
  
  

Gene name	lspA
Synonyms	lsp
Essential	no
Product	signal peptidase II
Function	protein secretion
Gene expression levels in SubtiExpress: lspA
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion
MW, pI	17 kDa, 9.133
Gene length, protein length	462 bp, 154 aa
Immediate neighbours	ylyA, ylyB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein secretion, membrane proteins

The gene

Basic information

• Locus tag: BSU15450

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Release of signal peptides from bacterial membrane prolipoproteins (according to Swiss-Prot)

• Protein family: peptidase A8 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q45479

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: lspA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

J Bengtsson, H Tjalsma, C Rivolta, L Hederstedt
Subunit II of Bacillus subtilis cytochrome c oxidase is a lipoprotein.
J Bacteriol: 1999, 181(2);685-8
[PubMed:9882689] [WorldCat.org] [DOI] (P p)