YkrK

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  • Description: transcription repressor of htpX expression

Gene name ykrK
Synonyms
Essential no
Product transcription repressor of htpX
Function regulation of membrane protein quality control
Gene expression levels in SubtiExpress: ykrK
MW, pI 26 kDa, 6.153
Gene length, protein length 699 bp, 233 aa
Immediate neighbours sspD, htpX
Sequences Protein DNA DNA_with_flanks
Genetic context
YkrK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkrK expression.png















Categories containing this gene/protein

Transcription factors and their control

This gene is a member of the following regulons

The YkrK regulon: htpX

The gene

Basic information

  • Locus tag: BSU13480

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
    • might be subject to autoregulation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ta-Hui Lin, Shih-Chien Huang, Gwo-Chyuan Shaw
Reexamining transcriptional regulation of the Bacillus subtilis htpX gene and the ykrK gene, encoding a novel type of transcriptional regulator, and redefining the YkrK operator.
J Bacteriol: 2012, 194(24);6758-65
[PubMed:23042994] [WorldCat.org] [DOI] (I p)

Bogumila C Marciniak, Hein Trip, Fabrizia Fusetti, Oscar P Kuipers
Regulation of ykrL (htpX) by Rok and YkrK, a novel type of regulator in Bacillus subtilis.
J Bacteriol: 2012, 194(11);2837-45
[PubMed:22447908] [WorldCat.org] [DOI] (I p)