RlmCD

• Description: rRNA methyltransferase
  
  

Gene name	rlmCD
Synonyms	yerS, yefA
Essential	no
Product	rRNA methyltransferase
Function	23S rRNA maturation
Gene expression levels in SubtiExpress: rlmCD
MW, pI	51 kDa, 5.707
Gene length, protein length	1377 bp, 459 aa
Immediate neighbours	dgkB, yefB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation

The gene

Basic information

• Locus tag: BSU06730

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: methylation of U747 and U1939 in 23S rRNA PubMed

• Protein family: COG2265

• Paralogous protein(s): YfjO

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31503

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: rlmCD PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Benoit Desmolaize, Céline Fabret, Damien Brégeon, Simon Rose, Henri Grosjean, Stephen Douthwaite
A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA.
Nucleic Acids Res: 2011, 39(21);9368-75
[PubMed:21824914] [WorldCat.org] [DOI] (I p)