YydA

• Description: similar to pseudouridine methyltransferase
  
  

Gene name	yydA
Synonyms
Essential	no
Product	similar to pseudouridine methyltransferase
Function	may be involved in maturation of 23S rRNA
Gene expression levels in SubtiExpress: yydA
MW, pI	17 kDa, 9.314
Gene length, protein length	477 bp, 159 aa
Immediate neighbours	yydB, yyzF
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation

This gene is a member of the following regulons

DnaA regulon

The gene

Basic information

• Locus tag: BSU40230

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine (according to Swiss-Prot)

• Protein family: RNA methyltransferase rlmH family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 1TO0

• UniProt: Q45601

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yydA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • DnaA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Rya Ero, Lauri Peil, Aivar Liiv, Jaanus Remme
Identification of pseudouridine methyltransferase in Escherichia coli.
RNA: 2008, 14(10);2223-33
[PubMed:18755836] [WorldCat.org] [DOI] (I p)

Elzbieta Purta, Katarzyna H Kaminska, Joanna M Kasprzak, Janusz M Bujnicki, Stephen Douthwaite
YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.
RNA: 2008, 14(10);2234-44
[PubMed:18755835] [WorldCat.org] [DOI] (I p)

Shu Ishikawa, Yoshitoshi Ogura, Mika Yoshimura, Hajime Okumura, Eunha Cho, Yoshikazu Kawai, Ken Kurokawa, Taku Oshima, Naotake Ogasawara
Distribution of stable DnaA-binding sites on the Bacillus subtilis genome detected using a modified ChIP-chip method.
DNA Res: 2007, 14(4);155-68
[PubMed:17932079] [WorldCat.org] [DOI] (P p)