LytH

• Description: differentiation-associated peptidoglycan hydrolase involved in endospore cortex maturation
  
  

Gene name	lytH
Synonyms	yunA, yutA
Essential	no
Product	peptidoglycan hydrolase
Function	endospore cortex maturation
Gene expression levels in SubtiExpress: lytH
MW, pI	39 kDa, 6.893
Gene length, protein length	1047 bp, 349 aa
Immediate neighbours	lipA, fisB
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall/ other, sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU32340

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M23B family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O32130

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: lytH PubMed

• Expression browser: lytH PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Gavin J Horsburgh, Abdelmadjid Atrih, Simon J Foster
Characterization of LytH, a differentiation-associated peptidoglycan hydrolase of Bacillus subtilis involved in endospore cortex maturation.
J Bacteriol: 2003, 185(13);3813-20
[PubMed:12813075] [WorldCat.org] [DOI] (P p)