GlgC

• Description: glucose-1-phosphate adenylyltransferase
  
  

Gene name	glgC
Synonyms
Essential	no
Product	glucose-1-phosphate adenylyltransferase
Function	glycogen biosynthesis
Gene expression levels in SubtiExpress: glgC
MW, pI	42 kDa, 4.857
Gene length, protein length	1140 bp, 380 aa
Immediate neighbours	glgD, glgB
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

miscellaneous metabolic pathways, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU30970

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose (according to Swiss-Prot)

• Protein family: bacterial/plant glucose-1-phosphate adenylyltransferase family (according to Swiss-Prot)

• Paralogous protein(s): GlgD

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39122

• KEGG entry: [3]

• E.C. number: 2.7.7.27

Expression and regulation

• Operon: glgB-glgC-glgD-glgA-glgP PubMed

• Expression browser: glgC PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

J A Kiel, J M Boels, G Beldman, G Venema
Glycogen in Bacillus subtilis: molecular characterization of an operon encoding enzymes involved in glycogen biosynthesis and degradation.
Mol Microbiol: 1994, 11(1);203-18
[PubMed:8145641] [WorldCat.org] [DOI] (P p)