RadC

• Description: probable DNA repair protein
  
  

Gene name	radC
Synonyms	ysxA
Essential	no
Product	probable DNA repair protein
Function	DNA repair
Gene expression levels in SubtiExpress: radC
MW, pI	25 kDa, 7.829
Gene length, protein length	693 bp, 231 aa
Immediate neighbours	mreB, maf
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination, genetic competence, cell envelope stress proteins (controlled by SigM, V, W, X, Y), phosphoproteins

This gene is a member of the following regulons

ComK regulon, SigM regulon

The gene

Basic information

• Locus tag: BSU28040

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: radC family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • phosphorylated on Arg-59 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: Cytoplasm (Homogeneous) PubMed

Database entries

• Structure:

• UniProt: Q02170

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: radC (according to DBTBS), radC-mreB-mreC-mreD-minC-minD PubMed

• Expression browser: radC PubMed

• Sigma factor: SigM PubMed

• Regulation:
  • expressed in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress (SigM) PubMed
  • expression is reduced in a SigV mutant PubMed

• Regulatory mechanism:
  • ComK: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed