YrpC

• Description: glutamate racemase
  
  

Gene name	yrpC
Synonyms
Essential	no
Product	glutamate racemase
Function	peptidoglycan precursor biosynthesis
Gene expression levels in SubtiExpress: yrpC
Metabolic function and regulation of this protein in SubtiPathways: Cell wall
MW, pI	29 kDa, 6.74
Gene length, protein length	795 bp, 265 aa
Immediate neighbours	yrpB, yrpD
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

The gene

Basic information

• Locus tag: BSU26810

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-glutamate = D-glutamate (according to Swiss-Prot)

• Protein family: aspartate/glutamate racemases family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2JFN (from Escherichia coli, 36% identity, 54% similarity) PubMed

• UniProt: O05412

• KEGG entry: [2]

• E.C. number: 5.1.1.3

Expression and regulation

• Operon:

• Expression browser: yrpC PubMed

• Sigma factor:

• Regulation: expressed only in minimal medium, not in complex medium PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Keitarou Kimura, Lam-Son Phan Tran, Yoshifumi Itoh
Roles and regulation of the glutamate racemase isogenes, racE and yrpC, in Bacillus subtilis.
Microbiology (Reading): 2004, 150(Pt 9);2911-2920
[PubMed:15347750] [WorldCat.org] [DOI] (P p)