CsbB

• Description: putative bactoprenol glycosyltransferase, general stress protein
  
  

Gene name	csbB
Synonyms	yfhN
Product	putative bactoprenol glycosyltransferase
Function	survival of ethanol and salt stress
Gene expression levels in SubtiExpress: csbB
MW, pI	37 kDa, 9.199
Gene length, protein length	987 bp, 329 aa
Immediate neighbours	yfhM, yfhO
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins

This gene is a member of the following regulons

SigB regulon, SigX regulon

The gene

Basic information

• Locus tag: BSU08600

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Additional information

• expression of CsbB in the absence of YfhO causes constitutive activation of SigM PubMed

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GtrB subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q45539

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: csbB PubMed

• Expression browser: csbB PubMed

• Sigma factor: SigB PubMed, SigX PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Hiromi Inoue, Daisuke Suzuki, Kei Asai
A putative bactoprenol glycosyltransferase, CsbB, in Bacillus subtilis activates SigM in the absence of co-transcribed YfhO.
Biochem Biophys Res Commun: 2013, 436(1);6-11
[PubMed:23632331] [WorldCat.org] [DOI] (I p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

X Huang, J D Helmann
Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search.
J Mol Biol: 1998, 279(1);165-73
[PubMed:9636707] [WorldCat.org] [DOI] (P p)

S Akbar, C W Price
Isolation and characterization of csbB, a gene controlled by Bacillus subtilis general stress transcription factor sigma B.
Gene: 1996, 177(1-2);123-8
[PubMed:8921856] [WorldCat.org] [DOI] (P p)