YfnI

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  • Description: polyglycerolphosphate lipoteichoic acid synthase, general stress protein, major secreted protein, required for survival at low temperature (4°C)

Gene name yfnI
Synonyms yetP, ltaSA
Essential no
Product minor lipoteichoic acid synthetase
Function biosynthesis of lipoteichoic acid
Gene expression levels in SubtiExpress: yfnI
MW, pI 73 kDa, 5.951
Gene length, protein length 1917 bp, 639 aa
Immediate neighbours yetO, yfnH
Sequences Protein DNA Advanced_DNA
Genetic context
YfnI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YfnI expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, cell envelope stress proteins (controlled by SigM, V, W, X, Y), phosphoproteins

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

  • Locus tag: BSU07260

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: LTA synthase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on (Thr-311 OR Ser-312) PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: yfnI (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Additional reviews: PubMed

Nathalie T Reichmann, Angelika Gründling
Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes.
FEMS Microbiol Lett: 2011, 319(2);97-105
[PubMed:21388439] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed