YxxG

• Description: immunity protein, protects the cell against the toxic activity of WapA
  
  

Gene name	yxxG
Synonyms	wapI
Essential	no
Product	immunity protein
Function	intercellular competition
Gene expression levels in SubtiExpress: yxxG
Interactions involving this protein in SubtInteract: YxxG
MW, pI	16 kDa, 4.424
Gene length, protein length	426 bp, 142 aa
Immediate neighbours	yxiF, wapA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, phosphoproteins,

This gene is a member of the following regulons

DegU regulon, YvrHb regulon

The gene

Basic information

• Locus tag: BSU39220

Phenotypes of a mutant

• severe growth defect PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • YxxG inhibits the toxic activity of WapA PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on (Tyr-102 OR Ser-105) PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • WapA-YxxG PubMed

• Localization:

Database entries

• Structure:

• UniProt: Q07836

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: wapA-yxxG PubMed

• Expression browser: yxxG PubMed

• Sigma factor:

• Regulation:
  • repressed at high salt concentration (DegU-P) PubMed

• Regulatory mechanism:
  • DegU-P: transcription repression PubMed
  • activated by YvrHb PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: