YaaH

• Description: general stress protein, survival of ethanol stress, SafA-dependent spore coat protein, spore cortex lytic protein
  
  

Gene name	yaaH
Synonyms	sleL
Essential	no
Product	N-acetylglucosaminidase
Function	survival of ethanol stress, protection of the spore
Gene expression levels in SubtiExpress: yaaH
MW, pI	48 kDa, 5.618
Gene length, protein length	1281 bp, 427 aa
Immediate neighbours	dgk, yaaI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon, SigE regulon, SpoIIID regulon

The gene

Basic information

• Locus tag: BSU00160

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • inner spore coat PubMed

Database entries

• Structure:

• UniProt: P37531

• KEGG entry: [3]

• E.C. number:

Additional information

required for survival of ethanol stress PubMed

Expression and regulation

• Operon: yaaH PubMed

• Expression browser: yaaH PubMed

• Sigma factor: SigE PubMed, SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed
  • expressed during sporulation in the mother cell (SigE, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription repression PubMed

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: