YloH
- Description: omega subunit of RNA polymerase
| Gene name | yloH |
| Synonyms | |
| Essential | no |
| Product | omega subunit of RNA polymerase |
| Function | unknown |
| Gene expression levels in SubtiExpress: yloH | |
| Interactions involving this protein in SubtInteract: YloH | |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation) | |
| MW, pI | 7 kDa, 5.513 |
| Gene length, protein length | 201 bp, 67 aa |
| Immediate neighbours | gmk, yloI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15690
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot)
- Protein family: RNA polymerase subunit omega family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- closely associated to RNA polymerase (RpoA(2)-RpoB-RpoC) PubMed
- Localization:
- closely associated with RNA polymerase involved in transcribing both mRNA and rRNA operons PubMed
Database entries
- Structure:
- UniProt: O35011
- KEGG entry: [2]
- E.C. number: 2.7.7.6
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
- present about at half the amount of core RNA polymerase PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
Additional publications: PubMed
L Minakhin, S Bhagat, A Brunning, E A Campbell, S A Darst, R H Ebright, K Severinov
Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc Natl Acad Sci U S A: 2001, 98(3);892-7
[PubMed:11158566]
[WorldCat.org]
[DOI]
(P p)
