EzrA

• Description: negative regulator of FtsZ ring formation
  
  

Gene name	ezrA
Synonyms	ytwP
Essential	no
Product	FtsZ-interacting protein
Function	control of FtsZ ring formation
Gene expression levels in SubtiExpress: ezrA
Interactions involving this protein in SubtInteract: EzrA
MW, pI	64 kDa, 4.757
Gene length, protein length	1686 bp, 562 aa
Immediate neighbours	braB, hisJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell division, membrane proteins

The gene

Basic information

• Locus tag: BSU29610

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ezrA family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • EzrA-UgtP PubMed
  • FtsZ-EzrA PubMed

• Localization: membrane associated PubMed

Database entries

• Structure:

• UniProt: O34894

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ezrA PubMed

• Expression browser: ezrA PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A805 ( ezrA::kan), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039] [WorldCat.org] [DOI] (I p)

David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248] [WorldCat.org] [DOI] (I p)