McpA

• Description: membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein
  
  

Gene name	mcpA
Synonyms
Essential	no
Product	methyl-accepting chemotaxis protein
Function	control of chemotaxis
Gene expression levels in SubtiExpress: mcpA
Interactions involving this protein in SubtInteract: McpA
MW, pI	72 kDa, 4.988
Gene length, protein length	1983 bp, 661 aa
Immediate neighbours	tlpB, tlpA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

• Locus tag: BSU31240

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): McpB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • deamination of Gln-586, Gln-593, and Gln-594 (by CheD) PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • CheD-McpA, deamination of Gln-586, Gln-593 and Gln-594 in McpA PubMed

• Localization:
  • cell membrane PubMed

Database entries

• Structure:

• UniProt: P39214

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tlpA-mcpA PubMed

• Expression browser: mcpA PubMed

• Sigma factor: SigD PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:
  • in minimal medium, McpA is present with 15,900 +/- 3,000 molecules per cell PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: