YhcF

• Description: similar to transcriptional regulator (GntR family)
  
  

Gene name	yhcF
Synonyms
Essential	no
Product	transcriptional regulator (GntR family)
Function	unknown
Gene expression levels in SubtiExpress: yhcF
MW, pI	13 kDa, 5.457
Gene length, protein length	363 bp, 121 aa
Immediate neighbours	yhcE, yhcG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control

The gene

Basic information

• Locus tag: BSU09060

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GntR family of transcription regulators

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3NEU (similar protein from Listeria innocua, 38% identity)

• UniProt: P54590

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yhbI-yhbJ-yhcA-yhcB-yhcC-yhcD-yhcE-yhcF-yhcG-yhcH-yhcI PubMed

• Expression browser: yhcF PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y (the half-life of the mRNA increases from 4 to 41 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947