PcrA
Revision as of 13:05, 10 August 2012 by Raphael2215 (talk | contribs)
- Description: ATP-dependent DNA helicase, facilitates unwinding of ICEBs1 DNA for horizontal transfer
Gene name | pcrA |
Synonyms | yerF |
Essential | yes PubMed |
Product | ATP-dependent DNA helicase |
Function | plasmid rolling-circle replication, conjugative transfer of ICEBs1 |
Gene expression levels in SubtiExpress: pcrA | |
Interactions involving this protein in SubtInteract: PcrA | |
MW, pI | 83 kDa, 5.767 |
Gene length, protein length | 2217 bp, 739 aa |
Immediate neighbours | pcrB, ligA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
DNA repair/ recombination, mobile genetic elements, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06610
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: uvrD-like helicase C-terminal domain (according to Swiss-Prot)
- Paralogous protein(s): YjcD
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2PJR (product complex, complex with sulphate ion, Geobacillus stearothermophilus), 1PJR (substrate complex, complex with DNA, Geobacillus stearothermophilus)
- UniProt: O34580
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Elisabeth Grohmann
Autonomous plasmid-like replication of Bacillus ICEBs1: a general feature of integrative conjugative elements?
Mol Microbiol: 2010, 75(2);261-3
[PubMed:19943906]
[WorldCat.org]
[DOI]
(I p)
Original Publications
Additional publications: PubMed