BioF
Revision as of 11:24, 20 April 2012 by 134.76.70.252 (talk)
- Description: 8-amino-7-oxononanoate synthase
Gene name | bioF |
Synonyms | |
Essential | no |
Product | 8-amino-7-oxononanoate synthase) |
Function | biosynthesis of biotin |
Metabolic function and regulation of this protein in SubtiPathways: Biotin | |
MW, pI | 42 kDa, 6.285 |
Gene length, protein length | 1167 bp, 389 aa |
Immediate neighbours | bioD, bioA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30220
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 6-carboxyhexanoyl-CoA + L-alanine = 8-amino-7-oxononanoate + CoA + CO2 (according to Swiss-Prot)
- Protein family: class-II pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P53556
- KEGG entry: [3]
- E.C. number: 2.3.1.47
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews: PubMed
Original publications