NagB

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  • Description: glucosamine-6-phosphate deaminase

Gene name nagB
Synonyms
Essential no
Product glucosamine-6-phosphate deaminase
Function N-acetylglucosamine utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism, Murein recycling
MW, pI 26 kDa, 5.717
Gene length, protein length 726 bp, 242 aa
Immediate neighbours nagA, nagR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NagB context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

cell wall degradation/ turnover, utilization of specific carbon sources

This gene is a member of the following regulons

NagR regulon

The gene

Basic information

  • Locus tag: BSU35020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3 (according to Swiss-Prot)
  • Protein family: NagB subfamily (according to Swiss-Prot)
  • Paralogous protein(s): GamA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced in the presence of N-acetylglucosamine (NagR) PubMed
  • Regulatory mechanism:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed