DapF

• Description: diaminopimelate epimerase
  
  

Gene name	dapF
Synonyms	yutL
Essential	yes PubMed
Product	diaminopimelate epimerase
Function	biosynthesis of lysine and peptidoglycan
Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr
MW, pI	30 kDa, 4.506
Gene length, protein length	852 bp, 284 aa
Immediate neighbours	sufA, yutK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, essential genes

The gene

Basic information

• Locus tag: BSU32170

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate (according to Swiss-Prot)

• Protein family: diaminopimelate epimerase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 2OTN (from Bacillus anthracis str. ames, 62% identity, 75% similarity)

• UniProt: O32114

• KEGG entry: [2]

• E.C. number: 5.1.1.7

Expression and regulation

• Operon:

• Expression browser: dapF PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: