Ffh

• Description: signal recognition particle (SRP) component
  
  

Gene name	ffh
Synonyms
Essential	yes PubMed
Product	signal recognition particle (SRP) component
Function	presecretory protein translocation
Interactions involving this protein in SubtInteract: Ffh
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion
MW, pI	49 kDa, 9.422
Gene length, protein length	1338 bp, 446 aa
Immediate neighbours	ylxM, rpsP
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

protein secretion, essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU15980

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GTP-binding SRP family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SecA-Ffh PubMed
  • Ffh-Scr in the signal recognition particle PubMed
  • Ffh-FtsY in the signal recognition particle PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:
  • 2XXA (complex Ffh-FtsY-Scr RNA, from E. coli) PubMed

• UniProt: P37105

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ylxM-ffh PubMed

• Expression browser: ffh PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: