YkcC

• Description: similar to dolichol phosphate mannose synthase
  
  

Gene name	ykcC
Synonyms
Essential	no
Product	unknown
Function	unknown
MW, pI	37 kDa, 8.011
Gene length, protein length	969 bp, 323 aa
Immediate neighbours	ykcB, htrA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

membrane proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

YclJ regulon, YrkP regulon

The gene

Basic information

• Locus tag: BSU12890

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GtrB subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YkcC is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed

• Localization: cell membrane (according to Swiss-Prot), Membrane (Heterogeneous) PubMed

Database entries

• Structure:

• UniProt: O34319

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ykcB-ykcC PubMed

• Expression browser: ykcC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • YclJ: transcription activation PubMed
  • YrkP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Elodie Marchadier, Rut Carballido-López, Sophie Brinster, Céline Fabret, Peggy Mervelet, Philippe Bessières, Marie-Françoise Noirot-Gros, Vincent Fromion, Philippe Noirot
An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach.
Proteomics: 2011, 11(15);2981-91
[PubMed:21630458] [WorldCat.org] [DOI] (I p)

Mitsuo Ogura, Kensuke Tsukahara, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YclJ.
Arch Microbiol: 2010, 192(7);569-80
[PubMed:20512483] [WorldCat.org] [DOI] (I p)

Mitsuo Ogura, Taku Ohsawa, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YrkP.
Biosci Biotechnol Biochem: 2008, 72(1);186-96
[PubMed:18175906] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)