KipI
- Description: inhibitor of KinA, control of the phosphorelay
Gene name | kipI |
Synonyms | ycsJ |
Essential | no |
Product | inhibitor of KinA |
Function | control of the phosphorelay, initiation of sporulation |
Interactions involving this protein in SubtInteract: KipI | |
Function and regulation of this protein in SubtiPathways: Phosphorelay | |
MW, pI | 26 kDa, 4.656 |
Gene length, protein length | 720 bp, 240 aa |
Immediate neighbours | ycsI, kipA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04080
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
Database entries
- UniProt: P60495
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
David A Jacques, David B Langley, Robert M G Hynson, Andrew E Whitten, Ann Kwan, J Mitchell Guss, Jill Trewhella
A novel structure of an antikinase and its inhibitor.
J Mol Biol: 2011, 405(1);214-26
[PubMed:21050859]
[WorldCat.org]
[DOI]
(I p)
Robert M G Hynson, Ann H Kwan, David A Jacques, Joel P Mackay, Jill Trewhella
1H, 13C and 15N backbone and side chain resonance assignments of the N-terminal domain of the histidine kinase inhibitor KipI from Bacillus subtilis.
Biomol NMR Assign: 2010, 4(2);167-9
[PubMed:20524093]
[WorldCat.org]
[DOI]
(I p)
David A Jacques, David B Langley, Cy M Jeffries, Katherine A Cunningham, William F Burkholder, J Mitchell Guss, Jill Trewhella
Histidine kinase regulation by a cyclophilin-like inhibitor.
J Mol Biol: 2008, 384(2);422-35
[PubMed:18823995]
[WorldCat.org]
[DOI]
(I p)
L Wang, R Grau, M Perego, J A Hoch
A novel histidine kinase inhibitor regulating development in Bacillus subtilis.
Genes Dev: 1997, 11(19);2569-79
[PubMed:9334321]
[WorldCat.org]
[DOI]
(P p)