SpoVS

• Description: required for dehydratation of the spore core and assembly of the coat, mutation increases SigD-dependent gene expression, might act via SinR
  
  

Gene name	spoVS
Synonyms
Essential	no
Product	unknown
Function	spore coat assembly, spore core dehydratation
MW, pI	8 kDa, 6.475
Gene length, protein length	258 bp, 86 aa
Immediate neighbours	ymdB, tdh
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation/ other

This gene is a member of the following regulons

SigH regulon

The gene

Basic information

• Locus tag: BSU16980

Expression

Phenotypes of a mutant

increased SigD-dependent gene expression, this might occur via SinR PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P45693

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVS PubMed

• Sigma factor: SigH PubMed

• Regulation:
  • expressed at the onset of stationary phase (SigH) PubMed

• Regulatory mechanism:

• Additional information:
  • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab

• Antibody: