MinJ

• Description: topological determinant of cell division
  
  

Gene name	minJ
Synonyms	yvjD, swrAB
Essential	no
Product	topological determinant of cell division
Function	cell division site selection
Interactions involving this protein in SubtInteract: MinJ
MW, pI	43 kDa, 9.057
Gene length, protein length	1191 bp, 397 aa
Immediate neighbours	yvkA, swrAA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

cell division, membrane proteins

The gene

Basic information

• Locus tag: BSU35220

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: The Min system prevents minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring, thereby ensuring that cell division occurs only once per cell cycle PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (MinC-MinD)-MinJ-DivIVA PubMed

• Localization:
  • forms rings at the division septum PubMed
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34375

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: swrAA-minJ PubMed

• Sigma factor: SigD PubMed, SigA PubMed

• Regulation:

• Regulatory mechanism:
  • DegU-P: transcription activation (SigA promoter) PubMed
• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Daniel Kearns, Indiana University, Bloomington, USA, homepage

Marc Bramkamp, University of Cologne, Cologne, Germany homepage

References

Reviews

Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039] [WorldCat.org] [DOI] (I p)