Program

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Monday March 14th 2011

13.50 - 14.00 Jörg Stülke Welcome and Introduction

Sunday, June 19, 2011 – Afternoon

Palazzo dei Congressi Auditorium

Physiology

CHAIR: Josef Deutscher

  • 2:15 – 2:30 T1, Elaine Milohanic, INRA and AgroParis Tech, Thiverval-Grignon, France
    • ManR regulates the expression of the main Listeria monocytogenes glucose/mannose transporter and uses a second glucose transporter as substrate sensor.
  • 2:30 – 2:45 T2, Boris Görke, Institute of Microbiology and Genetics, George-August University of Göttingen, Göttingen, Germany
    • Crh, the homolog of the phosphor-carrier protein HPr, regulates a glycolytic bypass in Bacillus subtilis.
  • 2:45 – 3:00 T3, Jean-Michel Jault, Institut de Biologie Structurale, Grenoble, France
    • The unusual activity of a GTPase from Bacillus subtilis, YphC (or EngA), involved in ribosome biogenesis.
  • 3:00 – 3:15 T4, Yuka Kazo, Laboratory of Molecular Genetics, Department of Life Science, College of Science, Rikkyo University, Tokyo, Japan
    • Analysis of dimerization of 70S ribosome, and yvyD gene during stationary phase in Bacillus subtilis.


Session I: Signalling, motility and biofilm formation

Chair: Eugenio Ferrari

  • 14:00 – 14:30 Daniel Kearns (Indiana University; Bloomington, USA): invited speaker
    • Flagellin homeostasis and morphogenic regulation of flagellar filament assembly in Bacillus subtilis
  • 14:30 – 14:45 Gyanendra P. Dubey, and Sigal Ben-Yehuda (Hebrew University; Jerusalem, Israel)
    • Intercellular nanotubes mediate bacterial communication
  • 14:45 – 15:00 Akos T. Kovacs, and Oscar P. Kuipers (University of Groningen, Netherlands)
    • Regulation of architecturally complex colony development in Bacillus subtilis
  • 15:00 – 15:15 Noël Molière, Janine Kirstein, and Kürşad Turgay (Freie Universität Berlin, Germany; and Northwestern University, Evanston, IL USA)
    • Involvement of Hsp100/Clp proteases in the motility development of Bacillus subtilis
  • 15:15 – 15:30 Sophie Bochmann, Benedikt Sattler, Sebastian W. Fuchs, Peter Kötter, and Karl-Dieter Entian (Goethe University, Frankfurt am Main, Germany)
    • Analysis of lantibiotic immunity and regulation in Bacillus subtilis
  • 15:30 – 15:45 Anna Staroń, Sebastian Dintner, Georg Fritz, Ulrich Gerland, Susanne Gebhard, and Thorsten Mascher (Ludwig-Maximilians-Universität München, Germany)
    • Peptide Antibiotic Sensing and Detoxification Modules of Bacillus subtilis: Stimulus Specificity, Signalling Interfaces and Regulatory Dynamics
  • 15:45 – 16:15 Coffee Break

Session II: Localisation and secretion

Chair: Thomas Wiegert

  • 16:15 – 16:30 Frank Bürmann, Nina Ebert, Suey van Baarle, and Marc Bramkamp (University of Cologne, Germany)
    • A bacterial dynamin-like protein mediating nucleotide independent membrane fusion
  • 16:30 – 16:45 Daniel Lopez (Institute for Molecular Infectious Diseases, Würzburg, Germany)
    • Targeting Lipid Rafts in Bacteria
  • 16:45 – 17:00 Tjeerd van Rij, Isabelle Maillet, Thomas Lapointe, Marcel Hillebrand, Sabrina Rodriguez, Jan Maarten van Dijl, and Zoltán Prágai (DSM Biotechnology Center, Delft, the Netherlands; DSM Nutritional Products, Basel, Switzerland; and UMCG-University of Groningen, the Netherlands)
    • Secretome of the industrial Bacillus amyloliquefaciens strain BZ9
  • 17:00 – 17:15 Simon Stammen, Claudia Korneli, Britta K. Müller, Tobias Knuuti, Constanze Finger, Ezequiel Franco-Lara, Dieter Jahn, and Rebekka Biedendieck (Technische Universität Braunschweig, Germany)
    • High-yield intra- and extracellular protein production using Bacillus megaterium
  • 17:15 – 17:30 Krzysztof Gizynski, Susanne Pohl and Colin R. Harwood (Newcastle University, Newcastle upon Tyne, United Kingdom)
    • The secondary protein secretion translocase of Bacillus anthracis

Session III: Replication–Cell cycle

Chair: Thorsten Mascher

  • 17:30 – 17:45 V. Bidnenko, S. McGovern, F. Lecointe, P. Noirot, and M.-F. Noirot-Gros (INRA, Jouy en Josas, France)
    • The B. subtilis negative controller of replication initiation YabA acts as a replication checkpoint
  • 17.45 – 18.00 Hamid Nouri, Anne-Françoise Monnier, Olivier Rannou, Monika Maciag, Solveig Fossum, Armelle Cabin-Flaman, Gregorz Wegrzyn, Vic Norris, Agnieszka Szalewska-Palasz, Panos Soultanas, Kirsten Skarstad, and Laurent Jannière (INRA, Jouy en Josas, France; Génopole Campus I, Evry, France; University of Nottingham, UK; University of Gdansk, Poland; Rikshospitalet, University of Oslo, Norway; and Faculté des Sciences de Rouen, Mont-Saint-Aignan, France)
  • 18.00 – 18.15 Vladimir Bidnenko, Lei Shi, Ahasanul Kobir, Magali Rault-Ventroux, Alain Trubuil, Marie-Françoise Noirot-Gros, and Ivan Mijakovic (INRA- AgroParisTech, and INRA, Jouy-en-Josas, France)
    • Phosphorylated bacterial recombinase checks chromosome integrity during spore formation
  • 18.15 – 18.30 Imrich Barák, Naďa Pavlendová, Ján Jamoroškovič, Anthony J. Wilkinson, and Katarína Muchová (Slovak Academy of Sciences, Bratislava, Slovakia; and University of York, UK)
    • Min system oscillation is adverse for asymmetric cell division during Bacillus subtilis sporulation

Tuesday March 15th 2011

Welcome to session: RNA biology of Bacillus

Session IV: RNA biology of Bacillus

Chair: Tony Wilkinson

  • 8.45 – 9.00 Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, the BaSysBio consortium, Michael Hecker, Uwe Völker, Philippe Bessières, and Philippe Noirot (INRA, Jouy-en-Josas, France; Ernst-Moritz-Arndt-Universität Greifswald, Germany; and INRA-AgroParisTech, Jouy-en-Josas, France)
    • Quantitative and qualitative analysis of the Bacillus subtilis whole-transcriptome across lifestyles
  • 9.00 – 9.15 Marc Schaffer, Anja Wiechert, Hanna Daniel, Claudia Schurmann, Georg Homuth, Michael Hecker, Volkmar Liebscher, and Ulrike Mäder (Ernst- Moritz-Arndt-University Greifswald, Germany)
    • Genome-wide analysis of mRNA half-lives in Bacillus subtilis
  • 9.15 - 9.30 Ruben A. T. Mars, Emma L. Denham, Pierre Nicolas, Philippe Noirot, Ulrike Mäder, Jan Maarten van Dijl and the BaSysBio and BACELL SysMo consortia (UMCG-University of Groningen, the Netherlands; INRA, Jouy-en-Josas, France; INRA-AgroParisTech, Jouy-en-Josas , France; and Ernst-Moritz-Arndt-University Greifswald, Germany)
  • 9.30 – 9.45 Matthias Gimpel, Heike Preis, Natalie Jahn, Nadja Heidrich, Andreas Licht, Ulrike Mäder, and Sabine Brantl (Friedrich-Schiller-Universität, Jena, Germany; Universität Würzburg, Germany; Jena Bioscience GmbH, Jena, Germany; Ernst-Moritz-Arndt-Universität Greifswald, Germany)
    • Two sRNA regulated systems from the Bacillus subtilis chromosome
  • 9.45 – 10.00 Martin Lehnik, Christina Herzberg, Marc Schaffer, Ulrike Mäder, Christine Diethmaier, and Jörg Stülke (Georg-August-Universität Göttingen, Germany; Ernst-Moritz-Arndt-University Greifswald, Germany)
    • Structural and functional association of RNases in Bacillus subtilis
  • 10.00 – 10.15 Karen Shahbabian, Ailar Jamalli, Léna Zig, and Harald Putzer (CNRS Paris, France)
    • RNase Y and RNase J, the two major players in mRNA metabolism in Bacillus subtilis
  • 10.15 – 10.30 Joseph A. Newman, Lorraine Hewitt, Cecilia Rodrigues, Alexandra Solovyova, Colin R. Harwood, and Richard J. Lewis (Newcastle University, Newcastle-upon-Tyne, U.K.)
    • Unusual, dual endo- and exo-nuclease activity in the degradosome explained by crystal structure analysis of RNase J1

Session IV; RNA biology of Bacillus; continued

Chair: Ulrike Mäder

  • 11.00 – 11.15 Katharina Schäfer, Ulrike Mäder, Georg Homuth, and Thomas Wiegert (University of Bayreuth, Germany; Ernst-Moritz-Arndt-University Greifswald, Germany; and University of Applied Sciences, Zittau/Görlitz, Germany)
    • Analysis of Rho-dependent termination of the Bacillus subtilis sigX-rsiX operon
  • 11.15 – 11.30 Anne R. Karow, Regula Aregger, and Dagmar Klostermeier (University of Basel, Biozentrum, Switzerland; and University of Muenster, Germany
    • Dissecting the mechanism of the DEAD box protein YxiN from Bacillus subtilis
  • 11.30 – 11.45 Hermann Hämmerle, Branislav Večerek, Ivo Hofacker, and Udo Bläsi (Max F. Perutz Laboratories, University of Vienna, Austria; Czech Academy of Sciences, Prague, Czech Republic; and Institute for Theoretical Chemistry, University of Vienna, Austria)
    • Identification of candidate Hfq targets in Bacillus subtilis
  • 11.45 – 12.00 Sandra Wiegand, Sascha Dietrich, and Heiko Liesegang (Georg-August-University of Göttingen, Germany)
    • Regulatory elements of Bacillus licheniformis DSM 13

Session V: Tools

Chair: Ulrike Mäder (continued)

  • 12.00 – 12.15 Jan Muntel, Vincent Fromion, Michael Hecker and Dörte Becher (Ernst-Moritz-Arndt-University of Greifswald, Germany; and INRA, Jouy-en-Josas, France)
    • New approach for global absolute protein quantification of B. subtilis
  • 12.15 – 12.30 Valérie Leclère, Maude Pupin; Walaa Hussein, Max Béchet, Frédérique Gancel, Marlène Chollet, Ségolène Caboche, and Philippe Jacques (Université de Lille Nord de France, Sciences et Technologies, Villeneuve d'Ascq, France)
    • Bioinformatics tools to decrypt non-ribosomal peptide diversity in Bacilli

Session VI: Regulation and Metabolism

Chair: Sabine Brantl

  • 14.00 – 14.15 Airat Kayumov, Annette Heinrich, Kseniya Fedorova, Olga Ilinskaya, and Karl Forchhammer (Kazan State University of Architecture and Engineering, Kazan, Russia; and Eberhard-Karls-Universität Tübingen, Germany)
  • 14.15 – 14.30 Jens Landmann, Ricarda Busse, Jörg Stülke, and Boris Görke (Georg-August-University of Göttingen, Germany)
    • Regulation of a glycolytic bypass by Crh, the homolog of the phospho-carrier protein HPr in Bacillus subtilis
  • 14.30 – 14.45 Alexander K.W. Elsholz, Dan Oertel, Katrin Gronau, Dörte Becher, Kürsad Turgay, Michael Hecker, and Ulf Gerth (Ernst-Moritz-Arndt-University of Greifswald, Germany; and Freie Universität Berlin, Germany)
    • Arginine phosphorylation modulates ClpC activity in Bacillus subtilis
  • 14.45 – 15.00 Ines Gruner, Anika March, Claudia Frädrich, and Elisabeth Härtig (Technical University of Braunschweig, Germany)
    • Regulation of anaerobic adaptation of Bacillus subtilis
  • 15.00 – 15.15 Marcus Miethke, Florian Peuckert, and Mohamed A. Marahiel (Philipps University of Marburg, Germany)
    • Ferric siderophore uptake and intracellular iron release in Bacillus subtilis and Bacillus halodurans
  • 15.15 – 15.30 S. Graf, and G. Unden (Universität Mainz, Germany)
    • The fumarate sensor DcuS of Geobacillus kaustophilus
  • 15.30 – 15.45 Ken-ichi Yoshida (Kobe University, Kobe, Japan)
    • Natural interconversion of inositol stereoisomers in bacteria?

Session VII: Cell wall and Sporulation

Chair: Dörte Becher

  • 16.15 – 16.30 Robyn T. Eijlander, and Oscar P. Kuipers (TI Food and Nutrition, Wageningen, the Netherlands; and University of Groningen, the Netherlands)
    • Studying Bacillus cereus sporulation and germination at the single cell level
  • 16.30 – 16.45 Eric Botella, Sebastian Hübner, and Kevin Devine (Trinity College Dublin, Ireland)
    • Cell envelope gene expression in phosphate limited Bacillus subtilis cells
  • 16.45 – 17.00 Anthony J. Wilkinson (University of York, UK)
    • Structural and interaction studies of an intercellular zipper mediating engulfment during sporulation in B. subtilis

Session VIII: Gram-positive pathogens

Chair: Imrich Barak

  • 17.00 – 17.15 Simen M. Kristoffersen, Nicolas J. Tourasse, Timothy D. Read, Brian Desany, Anne-Brit Kolstø, and Ole Andreas Økstad (School of Pharmacy, University of Oslo, Norway; Emory University School of Medicine, Atlanta, GA, USA; and Life Sciences, A Roche Company, Branford, USA)
    • Eighteen interspersed DNA repeat elements in the Bacillus cereus group promote genome dynamics and plasticity, and may confer global and local effects on neighbour gene transcription
  • 17.15 – 17.30 Susanne Pohl, Wang Yung Tu, Nigel Robinson, Kevin Waldron, and Colin Harwood (Newcastle University, Newcastle upon Tyne, United Kingdom)
    • The superoxide oxidative stress response of Bacillus anthracis
  • 17.30 – 17.45 Vahid Farshchi Andisi, Anne de Jong, Oscar P. Kuipers, and Jetta J.E. Bijlsma (UMCG-University of Groningen, the Netherlands; and University of Groningen, the Netherlands)
    • Identification of a Streptococcus pneumoniae protein involved in resistance to oxidative stress
  • 17.45 – 18.00 Annette Dreisbach, Magdalena M. van der Kooi-Pol, Andreas Otto, Katrin Gronau, Hendrik P. J. Bonarius, Hans Westra, Herman Groen, Dörte Becher, Michael Hecker, and Jan Maarten van Dijl (UMCG-University of Groningen, the Netherlands; Ernst-Moritz-Arndt-Universität, Greifswald, Germany; and IQ Therapeutics, Groningen, the Netherlands)
    • Profiling of global interactions between human serum proteins and the Staphylococcus aureus cell surface


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