PreQ1 riboswitch

This riboswitch controls the expression of the queC-queD-queE-queF operon in response to the availability of queuosine. In the absence of queuosine, the riboswitch allows transcriptional antitermination.

Structure of this riboswitch

Qi Zhang, Mijeong Kang, Robert D Peterson, Juli Feigon
Comparison of solution and crystal structures of preQ1 riboswitch reveals calcium-induced changes in conformation and dynamics.
J Am Chem Soc: 2011, 133(14);5190-3
[PubMed:21410253] [WorldCat.org] [DOI] (I p)

Mijeong Kang, Robert Peterson, Juli Feigon
Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA.
Mol Cell: 2009, 33(6);784-90
[PubMed:19285444] [WorldCat.org] [DOI] (I p)

Daniel J Klein, Thomas E Edwards, Adrian R Ferré-D'Amaré
Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase.
Nat Struct Mol Biol: 2009, 16(3);343-4
[PubMed:19234468] [WorldCat.org] [DOI] (I p)

Adam Roth, Wade C Winkler, Elizabeth E Regulski, Bobby W K Lee, Jinsoo Lim, Inbal Jona, Jeffrey E Barrick, Ankita Ritwik, Jane N Kim, Rüdiger Welz, Dirk Iwata-Reuyl, Ronald R Breaker
A riboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domain.
Nat Struct Mol Biol: 2007, 14(4);308-17
[PubMed:17384645] [WorldCat.org] [DOI] (P p)