ProG
- Description: 1-pyrroline-5-carboxylate dehydrogenase, the precise role of ProG is unknown
| Gene name | proG |
| Synonyms | ykeA, yzcA |
| Essential | no |
| Product | 1-pyrroline-5-carboxylate dehydrogenase |
| Function | biosynthesis of proline |
| Metabolic function and regulation of this protein in SubtiPathways: Pro, Stress | |
| MW, pI | 30 kDa, 4.914 |
| Gene length, protein length | 816 bp, 272 aa |
| Immediate neighbours | htrA, dppA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU12910
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H (according to Swiss-Prot)
- Protein family: pyrroline-5-carboxylate reductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: Q00777
- KEGG entry: [3]
- E.C. number: 1.5.1.2
Additional information
Expression and regulation
- Operon: proG PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
