YvrI

• Description: RNA polymerase sigma factor YvrI
  
  

Gene name	yvrI
Synonyms	sigO
Essential	no
Product	co-sigma factor with YvrHa
Function	RNA polymerase sigma factor
MW, pI	20.76 kDa, 9.36
Gene length, protein length	531 bp, 176 aa
Immediate neighbours	yvrHa, yvrJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription, sigma factors and their control, acid stress proteins (controlled by YvrI-YvrHa)

This gene is a member of the following regulons

YvrHb regulon, YvrI-YvrHa regulon

The gene

Basic information

• Locus tag: BSU33230

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: contains a DNA-binding helix-turn-helix motif (HTH) and the region 4.2 of Sigma factors PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YvrI-RpoB PubMed, YvrI-YvrHa PubMed

• Localization:

Database entries

• Structure:

• UniProt: O34843

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yvrI-yvrHa PubMed

• Sigma factor: YvrI-YvrHa PubMed

• Regulation: induced by acidic growth conditions PubMed

• Regulatory mechanism: activated by YvrHb PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage