GlgC

• Description: glucose-1-phosphate adenylyltransferase
  
  

Gene name	glgC
Synonyms
Essential	no
Product	glucose-1-phosphate adenylyltransferase
Function	glycogen biosynthesis
MW, pI	42 kDa, 4.857
Gene length, protein length	1140 bp, 380 aa
Immediate neighbours	glgD, glgB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

miscellaneous metabolic pathways, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU30970

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose (according to Swiss-Prot)

• Protein family: bacterial/plant glucose-1-phosphate adenylyltransferase family (according to Swiss-Prot)

• Paralogous protein(s): GlgD

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39122

• KEGG entry: [3]

• E.C. number: 2.7.7.27

Expression and regulation

• Operon: glgB-glgC-glgD-glgA-glgP PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

J A Kiel, J M Boels, G Beldman, G Venema
Glycogen in Bacillus subtilis: molecular characterization of an operon encoding enzymes involved in glycogen biosynthesis and degradation.
Mol Microbiol: 1994, 11(1);203-18
[PubMed:8145641] [WorldCat.org] [DOI] (P p)